贝投体育8059

2025/01--， 青年研究员。

2022/12--, LC8乐橙体育特聘研究岗位G2。

2013/12--，副研究员。?

2010/02--，贝投体育8059工作。???

2006/09-2010/01，LC8乐橙体育动物研究贝投体育8059，博士。???

2003/09-2006/06，北京师范大学，硕士。?

1999/09-2003/06，海南师范大学，本科。??

解析蝾螈类超大基因组与再生性状演化的机制

1. 基因组大小巨变的演化过程

从水生到陆生的转变是脊椎动物演化史上的一次重大飞跃。在这一过程中，基因组大小为何发生了巨变，以及这一变化与四足动物遗传性状创新之间的关系，成为一个极具吸引力的前沿科学问题。

通过挑选典型的水陆过渡类群，深入研究超大基因组（>10 Gb）中转座子这一最丰富分布最广元件的动态及宿主的响应(如表观修饰)，可以揭示转座子与功能基因的协同进化关系，从而探索转座子的功能多样性及其潜在的应用价值。

2. 再生性状的内在调控机制

与成体蛙类、爬行类、鸟类与哺乳类不同，蝾螈类具有惊人的再生能力，受伤后能完美修复几乎贝投体育8059有的器官，包括四肢、尾巴、眼睛、心脏、肺、肾脏甚至大脑。然而不同种类的蝾螈，以及同种但发育阶段不同的蝾螈，其再生性状存在显著差异。

通过选取不同支系和发育阶段的蝾螈，从转座子的调控入手，深入挖掘促进或阻抑再生的关键因子，旨在从独特的生物学角度为组织和器官的修复提供可行的策略。

3. 关键类群遗传多样性的保护策略

蝾螈类是脊椎动物中进化最独特且濒危地位最高的类群，尽管它们已存在上亿年，并具备令人惊奇的再生能力，但目前约有70%的物种面临灭绝威胁，65%的物种被列为国家级重点保护动物。

针对这些旗舰物种，研究其遗传多样性的形成机制及适应力的维持机制，不仅支撑生物多样性保护的国家战略，还能满足履行国际公约的重大需求。

热烈欢迎有志于达尔文医学、动物世界探秘的博士后、硕士生、博士生加入！

1. 国家自然科学基金面上：超大基因组蝾螈中转座子的时空表达及沉默机制研究，58万，2022/01-2025/12（主持）

2. 国家自然科学基金面上：中国大鲵性选择与交配制度的机制研究，29.4万，2016/01-2017/12（主持）?

3. 国家自然科学基金青年项目：大鲵洞穴种群的保护遗传学研究，25万，2013/01-2015/12（主持）?

4. 国家重点研发计划“野鸟携带病原检测”，子课题32.5万，2024/12-2027/11（主持）

5. 国家林业和草原局揭榜挂帅项目：野生动植物和古树名木鉴定技术及系统研发，子课题80万，2023/01-2026/12（主持）

6. 四川省人社厅留学人员科技活动择优资助项目：中国大鲵超大基因组的景观研究，5万 ，2022年（主持）

7. 伦敦动物研究贝投体育8059国际合作项目：川渝大鲵资源调查，11.4万，2014-2016 （主持）

8. LC8乐橙体育西部之光西部博士项目：基于转录组测序寻找繁殖期大鲵雌雄差异表达的基因及性别分子标记的开发，10万 ，2013/01-2015/12（主持）

9. 四川省科技厅应用基础项目：盆周山地大鲵繁殖的生态需求与原产地保护技术，18万，2012/01-2014/12（主持）

10. 乡城县林业和草原局政府采购项目：佛珠峡保护区与尼丁大峡谷保护区总体规划，191万，2023/08-2026/12（主持）

11. 泸定县林业和草原局政府采购项目：四川省二郎山省级森林公园陆地野生动物多样性专项调查，49.98万，2023/01-2023/12（主持）

12. 四川贡嘎山国家级自然保护区横向项目：贡嘎山两栖爬行动物调查与鸟类监测，58.7万，2017-2018（主持）

13. 中国环境科学院横向项目：康定县鸟类多样性调查与评估项目，70万，2016-2018（主持）?

14. 生态环境部生物多样性保护专项：四川生物多样性示范观测，243.7万，2011-2022（主持）?

15. 横向委托项目：XX工程影响区陆生生态环境调查和研究项目(鸟兽类群调查评估)，55万，2024/06-2029/03（主持）?

·1. Xuanzeng Liu, Jie Wang*, Yuan Huang*. 2026. Formation and maintenance of genome gigantism. Trends in Genetics. online, https://www.sciencedirect.com/science/article/pii/S016895252600003X

·2.?Jie Wang*, Guangpu Zhang, Cheng Sun, Liming Chang, Yingyong Wang, Xin Yang, Guiying Chen, Michael W. Itgen, Ava Haley,?Jiaxing?Tang*,?Rachel Lockridge Mueller*. 2025. DNA gains and losses in gigantic genomes do not track differences in transposable element-host silencing interactions. Communications Biology, 8, 704.

3.?Chen Yang, Jian Mou, Jiang Qiao, Guangfa Ruan, Yong Jiang,?Jie Wang*. 2025. Assessing the impact of elevation and seasonality on the detection of medium- to large-sized mammals by camera traps. Integrative Zoology, 20, 1056-1060.

4.?Shuai Tan^#,?Weiye Deng^#, Pengzhen Ji, Cheng Li, Jianping Jiang,?Zhuo?Chen*,?Jie Wang*. 2025. Amphibian roadkill investigation in the Qinling Mountains instantly after a night-rain in summer. Asian Herpetological Research, 16(1), 75-81.

5.?Jiang Qiao^#,?Pengzhen Ji^#, Qian Li, Zongliang Qian, Xuqin Li, Guangfa Ruan,?Yong Jiang*,?Jie Wang*. 2024. Habitat suitability analysis of wolves (Canis lupus) in the Gongga Mountains, Sichuan Province. Acta Theriologica Sinica, 44(6), 762-770. (in Chinese)

6.?Yuetong Zhou, Jiao Wang, Hong Chen, Jiang Qiao, Xiao’ao Zheng,?Yan?Huang*,?Jie Wang*. 2024. Chinese red panda found in alpine scree at 4939 m altitude in Gongga Mountains, Sichuan Province, China. Chinese Journal of Applied and Environmental Biology, 30(3), 664-665.?(in Chinese)

7.?Jiaxing Tang^#,?Jiaxin Cui^#, Gang Wang^#, Yong Jiang, Huaming Zhou, Jianping Jiang, Feng Xie,?Jie Wang*,?Guiying Chen*. 2024. Two-dimensional amphibian diversity along a 3500 m elevational gradient at the eastern edge of Qinghai-Xizang Plateau. Animals, 14, 1723.

8.?Qunmei Long, Zhizhe Tang, Jiaxing Tang, Haicheng Zhang,?Qinghua?Luo*,?Jie Wang*. 2024. Molecular sex identification and gonadal morphology of?Andrias davidianus?juveniles. Chinese Journal of Zoology, 59, 217-224. (in Chinese)

·9.?Jie Wang*, Liang Yuan, Jiaxing Tang, Jiongyu Liu, Cheng Sun, Michael W. Itgen, Guiying Chen, Stanley K. Sessions,?Guangpu Zhang*,?Rachel Lockridge Mueller*. 2023. Transposable element and host silencing activity in gigantic genomes. Frontiers in Cell and Developmental Biology, 11: 1124374.

10.?Chen Yang, Siheng Chen,?Jie Wang*. 2023. Ontogenetic colour change in the tail of Blue-tailed skinks (Plestodion elegans). Ecology and Evolution, 13: e10152.

11.?Jiang Qiao^#,?Xiaoli Gong^#, Wei Jia, Guoqing Jia, Yong Jiang, Huaming Zhou, Jiaqi Li,?Anxiang Wen*,?Jie Wang*. 2023. Distribution, group size and activity rhythm of the wolf (Canis lupus) in the Gongga Mountains, Sichuan Province. Acta Theriologca Sinica, 43(3): 248-257. (in Chinese)

12.?Qian Li, Wei L?, Xiao’ao Zheng, Lihua Zhou, Yi Zhang, Meng Wu, Faliang Shao, Huaming Zhou,?Jie Wang*. 2023. Black-necked crane,?Grus nigricollis, had stopover in Jiulong and Luding counties, Sichuan province, China. Journal of Applied and Environmental Biology, 29, 1498-1500. (in Chinese)

13.?Jiang Qiao, Guoqing Jia, Huaming Zhou, Lin Gong, Yong Jiang, Nengwen Xiao, Xiaoqi Gao, Anxiang Wen*,?Jie Wang*. 2022. Mammal and bird diversity recorded with camera traps in Gongga Mountain National Nature Reserve, Sichuan, China. Biodiversity Science, 30, 20395.?(in Chinese)

14.?Jiang Qiao, Guoqing Jia, Yong Jiang, Anxiang Wen,?Jie Wang*. 2022. Asiatic golden cat (Pardofelis temminckii) occurred in Gongga Mountains, Sichuan Province. Chinese Journal of Zoology, 57, 235,255.?(in Chinese)

·15.?Jie Wang, Ping Liu, Jiang Chang, Cheng Li,?Feng Xie*,?Jianping Jiang*. 2022. Development of an eDNA metabarcoding tool for survey of the world’s largest amphibian. Current Zoology, 68, 608-614.?

·16.?Jie Wang*, Michael W. Itgen, Huiju Wang, Yuzhou Gong, Jianping Jiang, Jiatang Li, Cheng Sun, Stanley K. Sessions,?Rachel Lockridge Mueller*. 2021. Gigantic genomes can provide empirical tests of TE dynamics models. Genomics, Proteomics & Bioinformatics, 19: 123-129.?

17.?Tingting Liao,?Yong Jiang*, Guiying Chen, Li Ding,?Jie Wang*. 2021. Yellow-throated marten?Martes flavigula?preyed on pearl-banded ratsnake?Euprepiophis perlacea?at Gongga Mountains, Sichuan province. Chinese Journal of Zoology, 56, 170,189. (in Chinese)

18.?Guangpu Zhang, Chen Yang, Limin Chen,?Guiying Chen*,?Jie Wang*. 2021. Complete mitochondrial genome of the spectacled parrotbill?Sinosuthora conspicillata?David, 1871 (Aves: Passeriformes: Sylviidae). Mitochondrial DNA Part B, 6, 3244-3245.

19.?Huaming Zhou, Meng Wu, Jing Li, Zhiming Li,?Jie Wang*. 2020. Population and distribution status of the Tibetan argali (Ovis hodgsoni) in the Shiqu County, Sichuan Province. Acta Theriologica Sinica, 40(4), 346-354.?(in Chinese)

20.?Wancai Xia, Faliang Shao, Guoqing Jia, Peng Cui, Huaming Zhou, Chen Yang,?Jie Wang*. 2020. Avian diversity, distribution, and fauna of the Gongga Mountains. Chinese Journal of Applied and Environmental Biology, 26(4), 1028-1034.? (in Chinese)

·21.?Jie Wang*, Hongxing Zhang, Fei Xie, Gang Wei,?Jianping Jiang*. 2017. Genetic bottlenecks of the wild Chinese giant salamander in karst caves. Asian Herpetological Research, 8(3), 174-183.?

22.?Guang Hao, Ping Cui, Chen Yang, Peng Cui,?Jie Wang*. 2016. Golden Eagle Aquila chrysaetos Nesting on a Cliff in Wanyuan, Sichuan. Chinese Journal of Zoology, 51, 923-924.?(in Chinese)

23.?Jie Wang*. 2015. Status of Japanese giant salamander and the enlightenment on the conservation of Chinese giant salamander. Chinese Journal of Applied and Environmental Biology, 21, 683-688.?(in Chinese)

24.?Jie Wang*, Jing Zhang, Xulin Li,?Jianping Jiang*. 2014. Isolation and characterization of 16 microsatellite loci for the giant salamander?Andrias?davidianus. Conservation Genetics Resources, 6, 367-368.?

25.?Jie Wang, Feng Xie, Gang Wang,?Jianping Jiang*. 2014. Group-spawning and simultaneously polyandry of a stream-dwelling frog?Feirana?kangxianensis. Asian Herpetological Research, 5(4), 240-244.?

26.?Jie Wang, Jing Zhang, Xin Yang, Xulin Li,?Jianping Jiang*. 2014. Isolation and characterization of 26 microsatellite loci for the frog?Feirana quadranus. Conservation Genetics Resources, 1, 57-58.?

27.?Jie Wang, Yun Fang, Siegfried Klaus,?Yue-Hua Sun*. 2012. Winter foraging strategy of the Chinese Grouse (Bonasa sewerzowi): ecological and physiological factors. Journal of Ornithology, 153, 257-264.?

28.?Jie Wang, Chen Yang, Lei Zhu, Chenxi Jia,?Yue-Hua Sun*. 2011. Sex-linkage identification of microsatellite TUT1. Chinese Journal of Applied and Environmental Biology, 17, 404-406.

29.?Jie Wang, Chenxi Jia, Songhua Tang, Yun Fang,?Yue-Hua Sun*. 2011. Breeding Biology of the Snowy-cheeked Laughingthrush (Garrulax sukatschewi). Wilson Journal of Ornithology, 123, 146-150.?

30.?Jie Wang,?Cuijuan Niu*, Chenxi Huang, Judie L. Rummer, Zhigang Xie. 2011. Compensatory growth in juvenile freshwater turtles,?Chinemys?reevesii, following feed deprivation. Journal of the World Aquaculture Society, 42, 82-89.??

31.?Jie Wang, Chen Yang, Nan Lu, Yun Fang,?Yue-Hua Sun*. 2010. Diet of Chinese grouse during preincubation. Wilson Journal of Ornithology, 122, 177-180.??

32.?Jie Wang, Chenxi Jia, Songhua Tang, Yun Fang,?Yue-Hua Sun*. 2010. Breeding of the Giant Laughingthrush (Garrulax maximus) at Lianhuashan, Southern Gansu, China. Wilson Journal of Ornithology, 122:388-391.??

33.?Jie Wang, Nan Lv, Chen Yang, Haizhong Chang,?Yue-Hua Sun*. 2010. Anatomy of Digestive System of the Chinese Grouse (Tetrastes sewerzowi). Chinese Journal of Zoology, 45, 122-126.?(in Chinese)

34.?Jie Wang,?Cuijuan Niu*. 2008. Effects of starvation on urinary nitrogen composition of juvenile Chinese Three-keeled Pond Turtles (Chinemys reevesii). Asiatic Herpetological Research, 11, 141-144.?

发明专利：

王杰, 谢锋, 江建平, 刘萍. 2021. 一种检测大鲵分布的环境DNA方法. 专利号，ZL 2021 1 0403977.8